Peptide Modification Services
Site-specific chemical and structural modifications to enhance peptide stability, bioavailability, and activity.
Service Overview
SynthAxis provides a full suite of peptide modification services designed to optimize your peptide candidates for downstream research or therapeutic development. Our modification workflows are tailored to each project, with careful attention to protecting group strategies and reaction selectivity.
Common modifications include N-terminal acetylation, C-terminal amidation, biotinylation, isotope labeling, cyclization, and PEGylation. All modified peptides are characterized by HPLC and mass spectrometry with certificates of analysis provided.
We work with both standard and difficult sequences, including hydrophobic, disulfide-containing, and phosphorylated peptides, ensuring high purity and functionality even for the most challenging targets.
Key Capabilities
Related Sub-Services
C-Terminal Modification
Amidation, esterification, and custom C-terminal capping for improved stability and membrane permeability.
N-Terminal Modification
Acetylation, formylation, succinylation, and other N-terminal caps for protease resistance.
Biotinylated Peptide Synthesis
Biotin-labeled peptides via NHS ester, maleimide, or direct Fmoc-biotin incorporation during SPPS.
Isotope Labeled Peptides
13C, 15N, and deuterium isotope-labeled peptides for quantitative proteomics and pharmacokinetic studies.