CDMO Service

Peptide Conjugation Services

Efficient and site-specific peptide conjugation for labeling, drug development, diagnostic development, and molecular functionalization.

Service Overview

SynthAxis offers comprehensive peptide conjugation services for pharmaceutical, diagnostic, and research applications. Our chemists employ diverse coupling strategies to attach peptides to drugs, oligonucleotides, fluorescent dyes, biotin, nanoparticles, and polymers with site-specific control.

We support both solution-phase and solid-phase conjugation approaches, with careful control over conjugation site, stoichiometry, and linker chemistry. Every conjugate is characterized by HPLC-MS, UV absorbance analysis, and functional assay support as needed.

Our capacity scales from research quantities to multi-gram production. All conjugation services include full documentation of synthetic procedures, analytical data, and batch release testing.

Key Capabilities

Peptide-drug conjugate (PDC) synthesis and characterization
Fluorescent dye labeling (FITC, TAMRA, Cy3, Cy5, FAM)
Peptide-siRNA conjugation with stable linker chemistries
Peptide-oligonucleotide conjugation for antisense delivery
Biotin conjugation for streptavidin-based detection systems
Maleimide, NHS ester, and click chemistry conjugation
Site-specific conjugation via cysteine, lysine, or N-terminus
PEG linker incorporation for improved pharmacokinetics
Cleavable and non-cleavable linker strategies
Full LC-MS characterization with purity ≥90%
Conjugate stability testing under multiple storage conditions
Scalable from mg discovery quantities to gram production